SCHEMBL3476404

SCHEMBL3476404

O=C1OC(=O)c2cc(-c3ccccc3S(=O)(=O)O)ccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 2/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ PDPK1 O15530 1/20 0.40
▸ ROCK2 O75116 1/20 0.40
▸ FES P07332 1/20 0.40
▸ FER P16591 1/20 0.40
▸ MARK3 P27448 1/20 0.40
▸ FLT3 P36888 1/20 0.40
▸ MAP4K2 Q12851 1/20 0.40
▸ PKN2 Q16513 1/20 0.40
▸ CDC42BPA Q5VT25 1/20 0.40
▸ SLK Q9H2G2 1/20 0.40
▸ IRAK4 Q9NWZ3 1/20 0.40
▸ PIM2 Q9P1W9 1/20 0.40
▸ PGAM1 P18669 1/20 0.40
▸ PTPRC P08575 4/20 0.39
▸ PTPN1 P18031 3/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ APAF1 O14727 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29003772 0.80 TDP1 (0.64) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL30085833 0.80 TDP1 (0.64) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL9169234 0.75 APP (0.47) TDP1PGAM1L3MBTL1MEN1LMNA
SCHEMBL9507935 0.75 GSTP1 (0.53) PGAM1LMNACYP1A2CYP2C9
SCHEMBL13786936 0.74 PGAM1 (0.43) ALOX15TDP1PGAM1PTPN1L3MBTL1
SCHEMBL29358248 0.74 ALOX15 (0.57) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL741462 0.74 ALOX15 (0.57) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL29359977 0.74 ALOX15 (0.57) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL169305 0.74 ALOX15 (0.57) ALOX15TDP1PTPRCPTPN1L3MBTL1
SCHEMBL29423347 0.74 ALOX15 (0.57) ALOX15TDP1PTPRCPTPN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354493-B2 Polyamic acid composition, polyimide endless belt, belt supporting member, fixing member and image formation device FUJI XEROX CO., LTD. (JP) 2013-01-15 — — US disclosed
US-20100233488-A1 POLYAMIC ACID COMPOSITION, POLYIMIDE ENDLESS BELT, BELT SUPPORTING MEMBER, FIXING MEMBER AND IMAGE FORMATION DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-16 — — US disclosed
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