Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | OGA | O60502 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246743 | 0.85 | KDM4E (0.51) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4724317 | 0.84 | NPC1 (0.48) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL10530529 | 0.78 | LMNA (0.53) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL5962506 | 0.77 | OGA (0.54) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL7546262 | 0.74 | OGA (0.51) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL4755801 | 0.74 | OGA (0.51) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1911514 | 0.73 | LMNA (0.56) | KDM4EALDH1A1LMNAL3MBTL1CYP2C19 | |
| SCHEMBL10498542 | 0.72 | LMNA (0.70) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6663539 | 0.72 | — | — | |
| SCHEMBL23863880 | 0.71 | OGA (0.49) | KDM4ERAB9AALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | claimed |
| WO-2010033168-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2010-03-25 | — | — | WO | disclosed |