Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | OGA | O60502 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476407 | 0.85 | KDM4E (0.48) | KDM4EALDH1A1TDP1SMN1; SMN2CYP2C19 | |
| SCHEMBL4724317 | 0.85 | NPC1 (0.48) | KDM4EALDH1A1TDP1SMN1; SMN2CYP2C19 | |
| SCHEMBL5962506 | 0.82 | OGA (0.54) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL11063217 | 0.81 | SMN1; SMN2 (0.62) | KDM4EALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL10530529 | 0.79 | LMNA (0.53) | KDM4EALDH1A1TDP1SMN1; SMN2CYP2C19 | |
| SCHEMBL10092714 | 0.76 | LMNA (0.50) | KDM4EALDH1A1TDP1SMN1; SMN2RAB9A | |
| SCHEMBL9006342 | 0.76 | RAD52 (0.52) | KDM4EALDH1A1TDP1CYP2C19LMNA | |
| SCHEMBL8838002 | 0.75 | HRH3 (0.53) | KDM4EALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL24220960 | 0.75 | SLC6A9 (0.40) | KDM4EALDH1A1RAB9ATP53MEN1 | |
| SCHEMBL7744888 | 0.75 | SLC6A9 (0.40) | KDM4EALDH1A1RAB9ATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118307525-A | Iridoid compound, preparation method thereof, pharmaceutical composition and application thereof | 安徽中医药大学 | 2024-07-09 | — | — | CN | claimed |
| CN-118307525-A | Iridoid compound, preparation method thereof, pharmaceutical composition and application thereof | 安徽中医药大学 | 2024-07-09 | — | — | CN | disclosed |