Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476292 | 0.89 | FAAH (0.53) | FAAHALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3476682 | 0.86 | FAAH (0.60) | FAAHALDH1A1NPC1GAAPKM | |
| SCHEMBL13436717 | 0.83 | FAAH (0.56) | FAAHALDH1A1NPC1GAAPKM | |
| SCHEMBL3475836 | 0.81 | NPC1 (0.56) | FAAHALDH1A1CLK4NPC1GAA | |
| SCHEMBL3477398 | 0.81 | FAAH (0.58) | FAAHALDH1A1USP2LMNACYP1A2 | |
| SCHEMBL3475438 | 0.80 | FAAH (0.57) | FAAHALDH1A1NPC1GAAPKM | |
| SCHEMBL3476299 | 0.79 | FAAH (0.73) | FAAHUSP2LMNACYP1A2CYP3A4 | |
| SCHEMBL13436686 | 0.79 | FAAH (0.54) | FAAHALDH1A1NPC1GAAPKM | |
| SCHEMBL13436779 | 0.79 | FAAH (0.56) | FAAHALDH1A1NPC1GAAPKM | |
| SCHEMBL3475856 | 0.78 | FAAH (0.65) | FAAHALDH1A1NPC1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |