Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.62 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476655 | 0.89 | FAAH (0.69) | FAAHPIK3CAHDAC6RPS6KA2GABRP | |
| SCHEMBL3475774 | 0.83 | FAAH (0.61) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL3476787 | 0.83 | FAAH (0.72) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL3474867 | 0.82 | FAAH (0.69) | FAAHPIK3CAHDAC6RPS6KA2HCRTR1 | |
| SCHEMBL3477435 | 0.82 | FAAH (0.75) | FAAHPIK3CAHDAC6RPS6KA2HCRTR1 | |
| SCHEMBL3476299 | 0.81 | FAAH (0.73) | FAAHPIK3CAHDAC6RPS6KA2HCRTR1 | |
| SCHEMBL13436724 | 0.80 | FAAH (0.63) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL3476698 | 0.77 | FAAH (1.00) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL3476876 | 0.77 | FAAH (0.77) | FAAHPIK3CAHDAC6RPS6KA2SSTR5 | |
| SCHEMBL3476090 | 0.77 | FAAH (0.61) | FAAHPIK3CAHDAC6SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |