Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516200 | 1.00 | HCAR2 (0.39) | HCAR2TLR4L3MBTL1TDP1MAPT | |
| SCHEMBL6516202 | 1.00 | HCAR2 (0.39) | HCAR2TLR4L3MBTL1TDP1MAPT | |
| SCHEMBL6516208 | 1.00 | HCAR2 (0.39) | HCAR2TLR4L3MBTL1TDP1MAPT | |
| SCHEMBL3476789 | 1.00 | HCAR2 (0.39) | HCAR2TLR4L3MBTL1TDP1MAPT | |
| SCHEMBL9868163 | 0.92 | MAPT (0.37) | HCAR2L3MBTL1TDP1MAPTATM | |
| SCHEMBL9868171 | 0.92 | MAPT (0.37) | HCAR2L3MBTL1TDP1MAPTATM | |
| SCHEMBL9868155 | 0.92 | MAPT (0.37) | HCAR2L3MBTL1TDP1MAPTATM | |
| SCHEMBL9868168 | 0.92 | MAPT (0.37) | HCAR2L3MBTL1TDP1MAPTATM | |
| SCHEMBL6522533 | 0.90 | PKM (0.36) | HCAR2L3MBTL1TDP1MAPTCYP2C9 | |
| SCHEMBL6522523 | 0.90 | PKM (0.36) | HCAR2L3MBTL1TDP1MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2087067-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | Merck Patent GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| EP-1179522-B1 | Liquid crystalline compound having a difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | CHISSO CORP (JP) | 2005-12-07 | — | — | EP | disclosed |
| US-6544604-B2 | Large dielectric anisotropy and low refractive anisotropy; for driving elements at low voltage | CHISSO CORPORATION (JP) | 2003-04-08 | — | — | US | disclosed |
| US-20020119260-A1 | Liquid crystalline compound having difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | JNC PETROCHEMICAL CORPORATION (JP) | 2002-08-29 | — | — | US | disclosed |
| EP-1179522-A1 | Liquid crystalline compound having a difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | CHISSO CORPORATION (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5032312-A | Liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119260-A1 | Liquid crystalline compound having difluoropropyleneoxy group as bonding group, liquid crystal composition and liquid crystal display element | OCIAD2, HCN2, OCIAD1 | HCAR2 2535/4885TLR4 3890/4885L3MBTL1 928/4885 |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | HCAR2 860/4885TLR4 1372/4885L3MBTL1 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.