Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.33 |
| ▸ | XPO1 | O14980 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477585 | 0.88 | LMNA (0.50) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL20162487 | 0.86 | TSHR (0.45) | LMNATSHRALDH1A1HCAR2SMN1; SMN2 | |
| SCHEMBL29117791 | 0.86 | LMNA (0.58) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL5716611 | 0.85 | ALDH1A1 (0.34) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL15610760 | 0.84 | LMNA (0.61) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL29177465 | 0.84 | LMNA (0.61) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL29096239 | 0.84 | LMNA (0.61) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL11171251 | 0.84 | LMNA (0.61) | LMNATSHRALDH1A1CES2CES1 | |
| SCHEMBL28066964 | 0.84 | ALDH1A1 (0.45) | LMNATSHRALDH1A1 | |
| SCHEMBL19471282 | 0.83 | LMNA (0.33) | LMNATSHRALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680172-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130245756-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | LILLY MING INTERNATIONAL, INC. | 2013-09-19 | — | — | US | disclosed |
| US-8430928-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20120245684-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| US-8222360-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20100211170-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010093823-A2 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| WO-2007037497-A1 | OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2007-04-05 | — | — | WO | disclosed |
| US-5100762-A | Radiation-sensitive polymer and radiation-sensitive composition containing the same | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 1992-03-31 | — | — | US | disclosed |