Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571435 | 0.89 | USP2 (0.46) | NR1H2USP2SMN1; SMN2GPR119RORC | |
| SCHEMBL120243 | 0.83 | USP2 (0.50) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL571118 | 0.78 | USP2 (0.46) | USP2SMN1; SMN2GPR119USP30RORC | |
| SCHEMBL20765932 | 0.77 | USP2 (0.47) | NR1H2USP2SMN1; SMN2GPR119ESR2 | |
| SCHEMBL14800964 | 0.77 | USP2 (0.52) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL995131 | 0.77 | USP2 (0.52) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL26409745 | 0.75 | USP2 (0.46) | NR1H2USP2SMN1; SMN2GPR119 | |
| Hydrochloric Acid SCHEMBL26689433 | 0.75 | USP2 (0.50) | NR1H2USP2SMN1; SMN2DDB1CRBN | |
| SCHEMBL30694561 | 0.75 | SCD5 (0.40) | NR1H2USP2SMN1; SMN2GPR119 | |
| SCHEMBL22405855 | 0.75 | HPGD (0.44) | USP2SMN1; SMN2GPR119USP30MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010132777-A2 | TREATMENT OF URINARY TRACT INFECTIONS WITH ANTIBACTERIAL AMINOGLYCOSIDE COMPOUNDS | ACHAOGEN, INC. (US) | 2010-11-18 | — | — | WO | disclosed |