Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887081 | 0.88 | GRIN2D (0.34) | DHODHALDH1A1AOC3 | |
| SCHEMBL11841129 | 0.86 | HIF1A (0.35) | DHODHALDH1A1 | |
| SCHEMBL348348 | 0.86 | LMNA (0.42) | ALDH1A1 | |
| SCHEMBL3178729 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL3672282 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL7186788 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL980256 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL868475 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL5204233 | 0.85 | HIF1A (0.37) | ALDH1A1 | |
| SCHEMBL3406450 | 0.85 | HIF1A (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE, CHI MING (CN) | 2022-12-08 | — | — | US | claimed |
| EP-4017936-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | Che, Chi Ming (HK) | 2022-06-29 | — | — | EP | claimed |
| WO-2021036978-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | CHE CHI MING (CN) | 2021-03-04 | — | — | WO | claimed |
| CN-112409243-A | Tetradentate ligand, gold (III) complex, and preparation method and application thereof | 支志明 | 2021-02-26 | — | — | CN | claimed |
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | claimed |
| US-9388135-B2 | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2-(1H)-ones | AERPIO THERAPEUTICS, INC. (US) | 2016-07-12 | — | — | US | claimed |
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. | 2015-08-20 | — | — | US | claimed |
| EP-2786985-A2 | Antagonists of the glucagon receptor | Metabasis Therapeutics, Inc. (US) | 2014-10-08 | — | — | EP | claimed |
| CN-101525497-B | pyrazoline pyridino-benzo coumarin fluorescent dye derivative and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2012-07-04 | — | — | CN | claimed |
| CN-101610995-A | Novel glucagon receptor antagonists | METABASIS THERAPEUTICS INC (US) | 2009-12-23 | — | — | CN | claimed |
| EP-2129654-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | Metabasis Therapeutics, Inc. (US) | 2009-12-09 | — | — | EP | claimed |
| CN-101525497-A | Pyrazoline pyridino-benzo coumarin fluorescent dye derivative and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS (CN) | 2009-09-09 | — | — | CN | claimed |
| CN-100519520-C | Process for preparing sulfidomethyl phenol derivatives | GUANGZHOU INST OF CHEMISTRY (CN) | 2009-07-29 | — | — | CN | claimed |
| WO-2008098244-A1 | NOVEL ANTAGONISTS OF THE GLUCAGON RECEPTOR | METABASIS THERAPEUTICS, INC. (US) | 2008-08-14 | — | — | WO | claimed |
| CN-1990467-A | Process for preparing sulfidomethyl phenol derivatives | GUANGZHOU INST OF CHEMISTRY (CN) | 2007-07-04 | — | — | CN | claimed |
| EP-0362649-B1 | Radiation-sensitive compositions and their use | BASF AG (DE) | 1994-03-02 | — | — | EP | claimed |
| EP-0362644-B1 | RADIATION-SENSITIVE COMPOSITIONS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1993-05-26 | — | — | EP | claimed |
| CN-118165031-A | Nitrile compound, electrolyte, secondary battery and device | 蔚来电池科技(安徽)有限公司 | 2024-06-11 | — | — | CN | disclosed |
| US-4139537-A | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds | COOPER LABORATORIES, INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4123538-A | (2-Amino-2-oxoethoxy)acetic acid compounds, compositions and methods | MCNEIL LABORATORIES, INCORPORATED (US) | 1978-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | CYP4B1, CYP8B1, HPD | DHODH 685/4885ALDH1A1 1501/4885AOC3 608/4885 |
| US-20220393118-A1 | TETRADENTATE LIGANDS, GOLD(III) COMPLEXES, PREPARATION METHOD AND USE THEREOF | PDCD2L, TTL, TTLL12 | DHODH 736/4885ALDH1A1 1432/4885AOC3 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.