Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7735789 | 1.00 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL7735799 | 1.00 | CYP1A2 (0.41) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL3477325 | 0.92 | LMNA (0.41) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL19722206 | 0.89 | CYP1A2 (0.45) | CYP1A2LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL10073833 | 0.89 | ESR2 (0.33) | CYP1A2LMNAMAPK1HTT | |
| SCHEMBL6750485 | 0.86 | TLR4 (0.41) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL31704075 | 0.86 | CYP1A2 (0.44) | CYP1A2LMNAMAPK1HTTALDH1A1 | |
| SCHEMBL9442488 | 0.86 | TLR4 (0.41) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL6458707 | 0.84 | CYP1A2 (0.58) | CYP1A2LMNAMAPK1HTTTLR4 | |
| SCHEMBL7507829 | 0.84 | CYP1A2 (0.58) | CYP1A2LMNAMAPK1HTTTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2087067-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | Merck Patent GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| US-6458433-B1 | ISOTOPE REPLACEMENT; OPTICAL DISPLAY | CHISSO CORPORATION (JP) | 2002-10-01 | — | — | US | disclosed |
| US-20020038858-A1 | Isotope replacement; optical display | JNC CORPORATION (JP) | 2002-04-04 | — | — | US | disclosed |
| US-6174459-B1 | HAVING BUTYLENE GROUP AND/OR A PROPYLENEOXY GROUP AND A 3,4-DIFLUOROPHENYL GROUP AND WHICH CAN EXPRESS SOME PHYSICAL PROPERTIES SUITABLE AS A LIQUID CRYSTAL DISPLAY MATERIAL | CHISSO CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0949232-A1 | DIFLUOROPHENYL DERIVATIVES, LIQUID-CRYSTAL COMPOUNDS, AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0922021-A1 | DIFLUOROPHENYL DERIVATIVE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007674-A1 | DIFLUOROPHENYL DERIVATIVE COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1998-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038858-A1 | Isotope replacement; optical display | IRS1, FES, IK | CYP1A2 2475/4885LMNA 3558/4885MAPK1 967/4885 |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | CYP1A2 1089/4885LMNA 461/4885MAPK1 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.