SCHEMBL3477155

SCHEMBL3477155

CCCCCN(CC(=O)O)CC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.59
APP P05067 2/20 0.59
EYA2 O00167 1/20 0.59
ACE P12821 1/20 0.59
TSHR P16473 5/20 0.56
BLM P54132 2/20 0.56
PMP22 Q01453 2/20 0.56
ALOX15 P16050 2/20 0.56
KDM4E B2RXH2 1/20 0.56
LMNA P02545 1/20 0.56
CHRM2 P08172 1/20 0.56
ADRA2A P08913 1/20 0.56
DRD1 P21728 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
CYP2C19 P33261 1/20 0.56
ADRA1A P35348 1/20 0.56
DRD3 P35462 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HRH3 Q9Y5N1 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2442110 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL2810757 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL2810353 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL8662917 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL2804385 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL15924210 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL2947339 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL1316624 0.98 TDP1 (0.56) TDP1APPEYA2ACETSHR
SCHEMBL251190 0.96 TSHR (0.65) TDP1APPEYA2ACETSHR
SCHEMBL28556079 0.96 TDP1 (0.54) TDP1APPEYA2ACETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3959191-A Novel hydrophobic polyurethane foams W. R. GRACE & CO. (US) 1976-05-25 US claimed
EP-3677246-B1 ANTIBACTERIAL ANTIFUNGAL COMPOSITION ADEKA CORP (JP) 2024-07-17 EP disclosed
US-10968299-B2 Copolymer and aqueous coating composition using same ADEKA CORPORATION (JP) 2021-04-06 US disclosed
WO-2020189365-A1 HAIR DYE COMPOSITION 株式会社ADEKA 2020-09-24 WO disclosed
US-20200214285-A1 ANTIBACTERIAL AND ANTIFUNGAL COMPOSITION ADEKA CORPORATION (JP) 2020-07-09 US disclosed
EP-3677246-A1 ANTIBACTERIAL ANTIFUNGAL COMPOSITION Adeka Corporation (JP) 2020-07-08 EP disclosed
EP-3231822-B1 COPOLYMER AND AQUEOUS COATING COMPOSITION USING SAME ADEKA CORP (JP) 2020-05-27 EP disclosed
EP-3099691-B1 PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS PROMEGA CORP (US) 2019-11-20 EP disclosed
US-9927430-B2 Pro-substrates for live cell applications PROMEGA CORPORATION (US) 2018-03-27 US disclosed
EP-3231822-A1 COPOLYMER AND AQUEOUS COATING COMPOSITION USING SAME Adeka Corporation (JP) 2017-10-18 EP disclosed
WO-2015116806-A1 PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS PROMEGA CORPORATION (US) 2015-08-06 WO disclosed
US-8513174-B2 Cleanser SHISEIDO COMPANY LTD. (JP) 2013-08-20 US disclosed
EP-2251403-B1 CLEANSING COMPOSITION SHISEIDO CO LTD (JP) 2012-08-29 EP disclosed
US-20100317555-A1 Cleanser SHISEIDO COMPANY LTD. (JP) 2010-12-16 US disclosed
EP-2251403-A1 CLEANSING COMPOSITION Shiseido Company, Ltd. (JP) 2010-11-17 EP disclosed
WO-2001092208-A1 METAL-CATALYSED CARBOXYMETHYLATION IN THE PRESENCE OF A PROMOTER MONSANTO TECHNOLOGY LLC (US) 2001-12-06 WO disclosed
US-6090345-A Phosphorus-containing compounds based on 1-hydroxypropane-1, 3-diphosphonic acid BAYER AG (DE) 2000-07-18 US disclosed
US-4523013-A 4-Acyl-2,6-dioxo-1-phenethyl piperozines SANOFI, S.A. (FR) 1985-06-11 US disclosed
US-4421693-A INSECTICIDES, MITICIDES OR NEMATOCIDES OTSUKA CHEMICAL CO., LTD. (JP) 1983-12-20 US disclosed
US-3991000-A WATER SOLUBLE INORGANIC COPPER SALT COLGATE-PALMOLIVE COMPANY (US) 1976-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200214285-A1 ANTIBACTERIAL AND ANTIFUNGAL COMPOSITION ERG28, CYP51A1, UGCG TDP1 4012/4885APP 3287/4885EYA2 2183/4885
US-20100317555-A1 Cleanser STS, SGMS1, PTDSS1 TDP1 975/4885APP 4341/4885EYA2 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.