Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | APP | P05067 | 2/20 | 0.61 |
| ▸ | EYA2 | O00167 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319897 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL11310530 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL8857559 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL11315528 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL8954314 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL8954395 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL3172648 | 0.98 | TSHR (0.62) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL3477155 | 0.96 | TDP1 (0.59) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL1976352 | 0.96 | TSHR (0.56) | TSHRTDP1BLMPMP22ALOX15 | |
| SCHEMBL19032432 | 0.94 | TSHR (0.56) | TSHRTDP1BLMPMP22ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1974720-B1 | Use of a vitreoscilla filiformis lipopolysaccharide fraction as an agent for stimulating the synthesis of anti-microbial skin peptides | OREAL (FR) | 2013-02-13 | — | — | EP | claimed |
| US-20090035294-A1 | LIPOPOLYSACCHARIDE FRACTIONS OF VITREOSCILLA FILIFORMIS USEFUL FOR STIMULATING THE SYNTHESIS OF ANTI-MICROBIAL PEPTIDES OF THE SKIN | L'OREAL (FR) | 2009-02-05 | — | — | US | claimed |
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | L'OREAL (FR) | 2007-03-15 | — | — | US | claimed |
| US-20070015840-A1 | Use of an alkyl ether of hydroxystilbene for the treatment of dry skin | L'OREAL (FR) | 2007-01-18 | — | — | US | claimed |
| EP-1413291-B1 | Use of 5-Cholesten-3 beta,25-diol-7-one for the treatment of dry skin or scalp | OREAL (FR) | 2006-05-03 | — | — | EP | claimed |
| EP-1374850-B1 | Cosmetic and/or dermatological composition containing at least one oxidation-sensitive hydrophilic active stabilised by at least one polymer or copolymer of maleic anhydride | OREAL (FR) | 2006-03-22 | — | — | EP | claimed |
| US-20040175342-A1 | Process of making and using composition containing oxidation-sensitive hydrophilic active principle and maleic anhydride copolymer | L'OREAL (FR) | 2004-09-09 | — | — | US | claimed |
| US-20040137023-A1 | 5-Cholesten-3beta, 25-diol-7-one, esters and ethers thereof, particularly for the treatment of dry skin and scalp | L'OREAL (FR) | 2004-07-15 | — | — | US | claimed |
| US-20030124161-A1 | Cosmetic and/or dermatological use of a composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer | L'OREAL (FR) | 2003-07-03 | — | — | US | claimed |
| EP-0629608-B1 | Process for preparing N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives | HAMPSHIRE CHEMICAL CORP (US) | 1998-10-28 | — | — | EP | claimed |
| EP-0861827-A2 | N-acyl-n,n'n'-ethylenediaminetriacetic acid derivatives and process for preparing the same | HAMPSHIRE CHEMICAL CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| US-5621008-A | TOPICAL DRUG FOR SKIN DISORDERS | AVON PRODUCTS, INC. (US) | 1997-04-15 | — | — | US | claimed |
| EP-0629608-A2 | N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives and process for preparing same | HAMPSHIRE CHEMICAL CORPORATION (US) | 1994-12-21 | — | — | EP | claimed |
| WO-2024137567-A1 | WET WIPE | THE PROCTER & GAMBLE COMPANY (US) | 2024-06-27 | — | — | WO | disclosed |
| US-12016944-B2 | Mixtures comprising a protein extract for the treatment of human skin and/or hair | SYMRISE AG (DE) | 2024-06-25 | — | — | US | disclosed |
| US-11980679-B2 | Sulfate free composition with enhanced deposition of scalp active | THE PROCTER & GAMBLE COMPANY (US) | 2024-05-14 | — | — | US | disclosed |
| US-5621008-A | TOPICAL DRUG FOR SKIN DISORDERS | AVON PRODUCTS, INC. (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0629608-A3 | N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives and process for preparing same. | HAMPSHIRE CHEMICAL CORP (US) | 1995-06-28 | — | — | EP | disclosed |
| EP-0629608-A2 | N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives and process for preparing same | HAMPSHIRE CHEMICAL CORPORATION (US) | 1994-12-21 | — | — | EP | disclosed |
| US-5284972-A | N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same | HAMPSHIRE CHEMICAL CORP. (US) | 1994-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070059269-A1 | Administration of 8-hexadecene-1,16-dicarboxylic acid for promoting cohesion of the epidermal horny layer | DSG1, CUTA, DSC1 | TSHR 4764/4885TDP1 2591/4885BLM 3456/4885 |
| US-20090035294-A1 | LIPOPOLYSACCHARIDE FRACTIONS OF VITREOSCILLA FILIFORMIS USEFUL FOR STIMULATING THE SYNTHESIS OF ANTI-MICROBIAL PEPTIDES OF THE SKIN | CUTA, LRBA, LTA | TSHR 1568/4885TDP1 4564/4885BLM 3867/4885 |
| US-11980679-B2 | Sulfate free composition with enhanced deposition of scalp active | POLR1C, STS, DPM1 | TSHR 3915/4885TDP1 966/4885BLM 3870/4885 |
| US-20040137023-A1 | 5-Cholesten-3beta, 25-diol-7-one, esters and ethers thereof, particularly for the treatment of dry skin and scalp | CYP46A1, HSD3B1, DHCR7 | TSHR 3771/4885TDP1 782/4885BLM 2382/4885 |
| US-20070015840-A1 | Use of an alkyl ether of hydroxystilbene for the treatment of dry skin | CYP8B1, HSD17B11, HSD17B1 | TSHR 2043/4885TDP1 1732/4885BLM 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.