SCHEMBL347754

SCHEMBL347754

CC(=O)CC(C)=Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 5/20 0.50
NOS3 P29474 4/20 0.50
CRHR1 P34998 3/20 0.47
ALDH1A1 P00352 2/20 0.45
MAPT P10636 5/20 0.43
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
HTR3E A5X5Y0 1/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
HTR3B O95264 1/20 0.41
PLAU P00749 1/20 0.41
HTR3A P46098 1/20 0.41
HTR3D Q70Z44 1/20 0.41
HTR3C Q8WXA8 1/20 0.41
NOS2 P35228 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5680219 1.00 NOS1 (0.50) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL347753 1.00 NOS1 (0.50) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL9201360 0.88 NOS1 (0.50) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL3924629 0.88 NOS1 (0.50) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL3924632 0.88 NOS1 (0.50) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL16627963 0.87 NOS1 (0.58) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL18544063 0.87 NOS1 (0.58) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL18543896 0.87 NOS1 (0.58) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL10811169 0.82 KMT2A (0.57) NOS1NOS3CRHR1ALDH1A1MAPT
SCHEMBL9195182 0.82 MAPT (0.45) NOS1NOS3CRHR1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
CN-107868150-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-11-10 CN claimed
CN-107868148-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-11-10 CN claimed
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868147-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
US-10662268-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2020-05-26 US claimed
US-20190256623-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST, AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-08-22 US claimed
EP-3517553-A1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF China Petroleum&Chemical Corporation (CN) 2019-07-31 EP claimed
CN-117304233-B Iridium metal complex, application thereof and organic electroluminescent device TSINGHUA UNIVERSITY (CN) 2026-05-26 CN disclosed
CN-117304233-A Iridium metal complex, application thereof and organic electroluminescent device 清华大学 2023-12-29 CN disclosed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
CN-107868150-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-107868148-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN disclosed
EP-1114836-A1 RESIN COMPOSITION AND PROCESS FOR PRODUCING THE SAME Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2001-07-11 EP disclosed
EP-0124231-B1 EPOXIDATION OF ETHYLENE BP Chemicals Limited (GB) 1987-07-22 EP disclosed
EP-0124231-A1 Epoxidation of ethylene BP Chemicals Limited (GB) 1984-11-07 EP disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4142061-A FOR STABILIZING COBALT CABONYL CATALYST CHEVRON RESEARCH COMPANY (US) 1979-02-27 US disclosed
US-4096191-A Hydroformylation of olefins using azoxy-dentated ligands CHEVRON RESEARCH COMPANY (US) 1978-06-20 US disclosed