Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.50 |
| ▸ | NOS3 | P29474 | 4/20 | 0.50 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201360 | 1.00 | NOS1 (0.50) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL3924629 | 1.00 | NOS1 (0.50) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL347754 | 0.88 | NOS1 (0.50) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL347753 | 0.88 | NOS1 (0.50) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL5680219 | 0.88 | NOS1 (0.50) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL18544063 | 0.87 | NOS1 (0.58) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL16627963 | 0.87 | NOS1 (0.58) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL18543896 | 0.87 | NOS1 (0.58) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL17489129 | 0.83 | RECQL (0.43) | NOS1NOS3CRHR1ALDH1A1MAPT | |
| SCHEMBL10811169 | 0.82 | KMT2A (0.57) | NOS1NOS3CRHR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503634-B1 | Novel terpene derivatives and process for preparing the same | EISAI CO LTD (JP) | 1995-12-27 | — | — | EP | claimed |
| US-20090018163-A1 | Substituted Heterocyclic Ethers and Their Use in CNS Disorders | BRISTOL-MYERS SQUIBB COMPANY | 2009-01-15 | — | — | US | disclosed |
| WO-2009009633-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018163-A1 | Substituted Heterocyclic Ethers and Their Use in CNS Disorders | CNR1, CNR2, PMP22 | NOS1 4422/4885NOS3 4103/4885CRHR1 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.