SCHEMBL16627963

SCHEMBL16627963

C/C(C/C(C)=N/c1ccccc1)=N\c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 7/20 0.58
NOS3 P29474 5/20 0.58
MAPT P10636 2/20 0.50
HTR3E A5X5Y0 2/20 0.48
HTR3B O95264 2/20 0.48
HTR3A P46098 2/20 0.48
HTR3D Q70Z44 2/20 0.48
HTR3C Q8WXA8 2/20 0.48
SLC22A2 O15244 1/20 0.48
SLC22A1 O15245 1/20 0.48
SLC22A3 O75751 1/20 0.48
PLAU P00749 1/20 0.48
LMNA P02545 2/20 0.46
CYP1A2 P05177 1/20 0.46
ALOX15 P16050 1/20 0.46
NFKB1 P19838 1/20 0.46
CYP2C19 P33261 1/20 0.46
BLM P54132 1/20 0.46
NOS2 P35228 3/20 0.45
CRHR1 P34998 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543896 1.00 NOS1 (0.58) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL18544063 1.00 NOS1 (0.58) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL18544025 0.88 ALDH1A1 (0.47) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL3924629 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL3924632 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL9201360 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL347754 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL347753 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL5680219 0.87 NOS1 (0.50) NOS1NOS3MAPTHTR3EHTR3B
SCHEMBL18543930 0.84 NOS1 (0.44) NOS1NOS3MAPTHTR3EHTR3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed