Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835155 | 0.81 | KMT2A (0.47) | TDO2KMT2ACHEK1MAPTCCNT1 | |
| SCHEMBL3477845 | 0.74 | ALOX5AP (0.36) | TDO2MAPTCYP11B2 | |
| SCHEMBL2409910 | 0.72 | KMT2A (0.45) | TDO2KMT2ACHEK1MAPTCCNT1 | |
| SCHEMBL14899993 | 0.72 | GPR84 (0.36) | TDO2MAPTCYP11B2 | |
| SCHEMBL2414762 | 0.70 | KMT2A (0.38) | KMT2ACHEK1 | |
| SCHEMBL13437106 | 0.70 | NAPRT (0.42) | TDO2KMT2ACDK9HASPIN | |
| SCHEMBL1278427 | 0.70 | KMT2A (0.45) | KMT2ACHEK1MAPTCCNT1CDK9 | |
| SCHEMBL12417811 | 0.69 | GPR84 (0.39) | TDO2MAPT | |
| SCHEMBL12417843 | 0.69 | GPR84 (0.40) | TDO2MAPTCYP11B2 | |
| SCHEMBL1833181 | 0.66 | NUDT1 (0.38) | TDO2MAPTCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024451-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |