Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CASP6 | P55212 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14899993 | 0.84 | GPR84 (0.36) | ALOX5APFEN1GPR84TDO2MAPT | |
| SCHEMBL12417811 | 0.81 | GPR84 (0.39) | GPR84TDO2MAPTNPC1HTT | |
| SCHEMBL12417843 | 0.80 | GPR84 (0.40) | GPR84TDO2MAPTCYP3A4CYP11B2 | |
| SCHEMBL1830980 | 0.78 | NAPRT (0.33) | — | |
| SCHEMBL2194154 | 0.76 | NAPRT (0.38) | MAPT | |
| SCHEMBL1830977 | 0.76 | SSTR4 (0.38) | — | |
| SCHEMBL4566391 | 0.75 | CHRM2 (0.32) | NPC1HTT | |
| SCHEMBL9969425 | 0.74 | NPC1 (0.38) | ALOX5APFEN1MAPTNPC1HTT | |
| SCHEMBL3477844 | 0.74 | TDO2 (0.33) | TDO2MAPTCYP11B2 | |
| SCHEMBL1830978 | 0.74 | DYRK1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024451-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |