SCHEMBL347785

SCHEMBL347785

[O]c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.67
TSHR P16473 1/20 0.67
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
MAOA P21397 1/20 0.56
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
GSTP1 P09211 1/20 0.52
SOS1 Q07889 1/20 0.52
CA9 Q16790 1/20 0.52
PARP10 Q53GL7 1/20 0.52
SRD5A2 P31213 1/20 0.50
MGLL Q99685 1/20 0.48
FFAR1 O14842 1/20 0.47
PGR P06401 1/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
IDH1 O75874 1/20 0.47
LMNA P02545 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129853 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL435149 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9212518 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL122719 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL3893562 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL11576945 0.85 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL9061108 0.82 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL2461810 0.82 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL4950525 0.82 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL12286 0.82 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108752412-B Boswellic acid derivatives and their use 沈阳药科大学 2020-10-13 CN claimed
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
CN-105085386-A Medical application of 2-(4-phenoxyphenoxy)fatty acyl pyridylamine UNIV HUNAN 2015-11-25 CN claimed
US-8710038-B2 Pyrazole kinase modulators and methods of use EXELIXIS, INC. (US) 2014-04-29 US claimed
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY 2007-10-11 US claimed
EP-0289919-B1 N-SUBSTITUTED AZOLES BASF Aktiengesellschaft (DE) 1993-03-17 EP claimed
EP-0412391-A1 Cyclopropane thiocarboxylic acid amides BASF Aktiengesellschaft (DE) 1991-02-13 EP claimed
EP-0049397-A1 A herbicidal composition AMERICAN HOECHST CORPORATION (US) 1982-04-14 EP claimed
US-4301295-A ANTILIPEMIC AND ANTICHOLESTEROL AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-11-17 US claimed
CN-118206421-A Dihydro fulvene derivative and preparation method thereof 河南省科学院化学研究所有限公司 2024-06-18 CN disclosed
EP-4327139-A1 METHOD FOR MANUFACTURING AN OPTICAL MATERIAL AND COMPOSITION USED IN THIS METHOD Mitsui Chemicals, Inc. (JP) 2024-02-28 EP disclosed
CN-116940867-A Method for manufacturing optical material and composition used in the method 三井化学株式会社 2023-10-24 CN disclosed
WO-2023190286-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2023-10-05 WO disclosed
WO-2022259985-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2022-12-15 WO disclosed
EP-0049436-A1 Process for producing highly stereoregular alpha-olefin polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-04-14 EP disclosed
US-4316993-A Process for the preparation of 4-phenoxy-phenols HOECHST AKTIENGESELLSCHAFT (DE) 1982-02-23 US disclosed
EP-0001267-B1 MASS COLORATION OF LINEAR POLYESTERS CIBA-GEIGY AG (CH) 1981-09-16 EP disclosed
US-4231918-A THIOINDIGO OR DIOXAZINE PIGMENT AND DYE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
EP-0001267-A1 Mass coloration of linear polyesters CIBA-GEIGY AG (CH) 1979-04-04 EP disclosed
US-3996191-A DIOXAZINE DYES CIBA-GEIGY AG (CH) 1976-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238669-A1 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES RELATED CONDITIONS GLP1R, GIPR, IAPP LTA4H 1569/4885TSHR 100/4885NR1H2 1202/4885
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method ASH2L, MLLT1, FRG1 LTA4H 1050/4885TSHR 3984/4885NR1H2 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.