Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | NAAA | Q02083 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789498 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10073435 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19844235 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19906406 | 0.95 | TSHR (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL16133527 | 0.94 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3477059 | 0.94 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL14907410 | 0.94 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL22679145 | 0.91 | TSHR (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9979757 | 0.91 | TSHR (0.43) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19844232 | 0.90 | THRB (0.46) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |
| US-9315728-B2 | Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film | JNC CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| US-8419973-B2 | Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100151154-A1 | Polymerizable liquid crystal composition and homeotropically-aligned liquid crystal film | CHISSO CORPORATION | 2010-06-17 | — | — | US | disclosed |
| US-20100143612-A1 | Polymerizable liquid crystal composition and homogeneous-aligned liquid crystal film | CHISSO CORPORATION | 2010-06-10 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2087067-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | Merck Patent GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | TSHR 3118/4885THRB 4144/4885ALDH1A1 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.