Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 15/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSK | P43235 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224680 | 1.00 | PTPRB (0.58) | PTPRBCTSSCTSK | |
| SCHEMBL6803159 | 0.94 | PTPRB (0.61) | PTPRBCTSSCTSK | |
| SCHEMBL3486971 | 0.94 | PTPRB (0.61) | PTPRBCTSSCTSK | |
| SCHEMBL3486972 | 0.94 | PTPRB (0.61) | PTPRBCTSSCTSK | |
| SCHEMBL6800353 | 0.92 | PTPRB (0.56) | PTPRBCTSSCTSK | |
| SCHEMBL6800348 | 0.92 | PTPRB (0.56) | PTPRBCTSSCTSK | |
| SCHEMBL5188418 | 0.88 | CTSS (0.72) | CTSSCTSK | |
| SCHEMBL7273440 | 0.88 | CTSS (0.72) | CTSSCTSK | |
| SCHEMBL5188769 | 0.88 | CTSS (0.72) | CTSSCTSK | |
| SCHEMBL6884640 | 0.87 | CTSS (0.55) | PTPRBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7769575-B2 | Three dimensional coordinates of HPTPbeta | Warner Chilcott, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| US-20100030487-A1 | THREE DIMENSIONAL COORDINATES OF HPTPbeta | Aerpio Pharmaceuticals, Inc. | 2010-02-04 | — | — | US | disclosed |
| US-7507568-B2 | Three dimensional coordinates of HPTPbeta | THE PROCTOR & GAMBLE COMPANY (US) | 2009-03-24 | — | — | US | disclosed |
| US-20040077065-A1 | Three dimensional coordinates of HPTPbeta | THE PROCTER & GAMBLE COMPANY | 2004-04-22 | — | — | US | disclosed |