Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.55 |
| ▸ | CTSK | P43235 | 5/20 | 0.55 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6884631 | 0.90 | CTSS (0.48) | CTSSCTSKBCL2PTPRBCTSL | |
| SCHEMBL13224680 | 0.87 | PTPRB (0.58) | CTSSCTSKPTPRB | |
| SCHEMBL3478075 | 0.87 | PTPRB (0.58) | CTSSCTSKPTPRB | |
| SCHEMBL5188769 | 0.85 | CTSS (0.72) | CTSSCTSKBCL2CTSLCTSB | |
| SCHEMBL7273440 | 0.85 | CTSS (0.72) | CTSSCTSKBCL2CTSLCTSB | |
| SCHEMBL5188418 | 0.85 | CTSS (0.72) | CTSSCTSKBCL2CTSLCTSB | |
| SCHEMBL3477448 | 0.82 | CTSS (0.62) | CTSSCTSKBCL2CTSLCTSB | |
| SCHEMBL6800348 | 0.81 | PTPRB (0.56) | CTSSCTSKPTPRBREN | |
| SCHEMBL6800353 | 0.81 | PTPRB (0.56) | CTSSCTSKPTPRBREN | |
| SCHEMBL3477645 | 0.81 | CTSS (0.58) | CTSSCTSKBCL2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077065-A1 | Three dimensional coordinates of HPTPbeta | THE PROCTER & GAMBLE COMPANY | 2004-04-22 | — | — | US | disclosed |