Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.30 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.30 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467415 | 0.82 | KMT2A (0.45) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL3472577 | 0.66 | OPRM1 (0.38) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL3478615 | 0.63 | KMT2A (0.41) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2781670 | 0.63 | ALDH1A1 (0.41) | POLBALDH1A1KDM4E | |
| SCHEMBL16191225 | 0.61 | HTT (0.51) | MAOAMAOB | |
| SCHEMBL3469152 | 0.61 | KMT2A (0.46) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL2154996 | 0.60 | KMT2A (1.00) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL9098061 | 0.60 | KMT2A (0.61) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL17950681 | 0.60 | KMT2A (0.66) | KMT2AMEN1POLBGAAMAPK1 | |
| SCHEMBL9097396 | 0.59 | EPHX2 (0.64) | KMT2AMEN1POLBGAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | disclosed |