Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MGAT2 | Q10469 | 5/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.48 |
| ▸ | MGAT1 | P26572 | 1/20 | 0.47 |
| ▸ | MGAT3 | Q09327 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780829 | 0.83 | GAA (0.59) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3469175 | 0.79 | GAA (0.56) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL2782035 | 0.78 | KMT2A (0.56) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL2781263 | 0.76 | GAA (0.53) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3478684 | 0.76 | MAPK1 (0.52) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL5332060 | 0.76 | ALDH1A1 (0.58) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL2782662 | 0.75 | GAA (0.49) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3469163 | 0.75 | CASP3 (0.55) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL3467433 | 0.74 | KMT2A (0.49) | MAPK1GAAKMT2AMEN1POLB | |
| SCHEMBL13196452 | 0.74 | GAA (0.50) | MAPK1GAAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010090680-A1 | SUBSTITUTED OXINDOLE CB2 AGONISTS | WYETH LLC (US) | 2010-08-12 | — | — | WO | claimed |