Edrophonium

Edrophonium

SCHEMBL34790

CC[N+](C)(C)c1cccc(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHE

The experimentally established mechanism targets of Edrophonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 6/20 1.00
TSHR P16473 4/20 1.00
OPRM1 P35372 1/20 1.00
BLM P54132 1/20 0.96
SMN1; SMN2 Q16637 1/20 0.96
CHRM2 P08172 2/20 0.44
CHRM1 P11229 2/20 0.44
CHRM3 P20309 2/20 0.44
ALDH1A1 P00352 4/20 0.44
CYP3A4 P08684 4/20 0.44
CA12 O43570 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
LMNA P02545 1/20 0.44
CA5A P35218 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
ENPP2 Q13822 1/20 0.38
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edrophonium SCHEMBL29627074 1.00 ACHE (1.00) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL8009388 1.00 ACHE (1.00) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL34789 0.98 ACHE (1.00) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL10893553 0.98 ACHE (0.96) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL19148596 0.98 ACHE (1.00) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL2462104 0.98 ACHE (1.00) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL10893551 0.96 ACHE (0.96) ACHETSHROPRM1BLMSMN1; SMN2
Edrophonium SCHEMBL4065806 0.89 ACHE (0.83) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL4611923 0.83 ACHE (0.71) ACHETSHROPRM1BLMSMN1; SMN2
SCHEMBL4611780 0.81 ACHE (0.68) ACHETSHROPRM1BLMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18124 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4736841-A1 A MUCOADHESIVE LAYER FOR BUCCAL ADMINISTRATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT IQ medical GmbH (DE) 2026-05-06 EP claimed
EP-4029690-B1 METAL-CLAD LAMINATE FOR FLEXIBLE ELECTRONIC DEVICES, AND FLEXIBLE ELECTRONIC DEVICE USING SAME NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-04-22 EP claimed
US-20260097063-A1 ANTI-C5 ANTIBODY/C5 IRNA DOSING REGIMENS FOR TREATING C5-ASSOCIATED DISEASES REGENERON PHARMA (US) 2026-04-09 US claimed
US-20260076872-A1 POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME SIO2 MEDICAL PRODUCTS LLC (US) 2026-03-19 US claimed
US-12570785-B2 Thermoplastic polyurethane resin elastomers MITSUBISHI CHEMICAL CORPORATION (JP) 2026-03-10 US claimed
EP-4665351-A1 IMPROVING GLYMPHATIC-LYMPHATIC EFFLUX University of Rochester (US) 2025-12-24 EP claimed
EP-4635489-A1 COMPOSITION FOR PREVENTING OR TREATING SIDE EFFECTS OF CHOLINESTERASE INHIBITORS Dr.Noah Biotech Inc. (KR) 2025-10-22 EP claimed
US-20250271426-A1 REDUCTION OF BITTER TASTE OF ACTIVE PHARMACEUTICAL INGREDIENTS AND RELATED ASSAYS AND SCREENING METHODS FIRMENICH INCORPORATED (US) 2025-08-28 US claimed
US-20250242092-A1 SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS SIO2 MEDICAL PRODUCTS INC (US) 2025-07-31 US claimed
EP-4249494-B1 A DRUG COMPRISING A RADICAL GENERATING CATALYST ACENET INC (JP) 2025-07-16 EP claimed
US-5010056-A Growth disorders PIERREL SPA (IT) 1991-04-23 US claimed
EP-0166724-B1 COMPOSITION FOR TREATING PEDICULOSIS SOFT SHEEN PRODUCTS, INC. (US) 1990-11-22 EP claimed
US-4952586-A FOR ANTAGONIZING NONDEPOLARIZING NEUROMUSCULAR BLOCKADE WHEN MUSCLE RELAXATION IS NOT NEEDED THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1990-08-28 US claimed
EP-0301392-A1 Pharmaceutical composition for intranasal administration comprising GH - Releasing hormone, a cholinergic agonist and in case a bile salt Pierrel S.p.A. (IT) 1989-02-01 EP claimed
US-4661509-A ENZYME INHIBITORS GORDON ARNOLD Z 1987-04-28 US claimed
US-4590166-A WASHING WITH WATER AND ALCOHOL THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1986-05-20 US claimed
EP-0166724-A1 COMPOSITION FOR TREATING PEDICULOSIS. SOFT SHEEN PRODUCTS INC (US) 1986-01-08 EP claimed
US-4562196-A ANTAGONIST OF MUSCLE RELAXANTS NELSON RESEARCH & DEVELOPMENT (US) 1985-12-31 US claimed
WO-1985002755-A1 METHOD AND COMPOSITION FOR TREATING PEDICULOSIS SOFT SHEEN PRODUCTS, INC. (US) 1985-07-04 WO claimed
US-4439427-A Method and composition for treating pediculosis SOFT SHEEN PRODUCTS, INC. (US) 1984-03-27 US claimed