Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 6/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | DHODH | Q02127 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27957021 | 0.83 | MAPT (0.54) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL2885791 | 0.82 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL12158147 | 0.76 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3046343 | 0.76 | ALDH1A1 (0.70) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL12296366 | 0.76 | MAPT (0.79) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3584407 | 0.75 | SMN1; SMN2 (0.80) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL12158131 | 0.75 | MAPT (0.84) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL18320945 | 0.75 | KDM4E (1.00) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL1541108 | 0.75 | MAPT (0.65) | MAPTALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL10288174 | 0.74 | CDC7 (0.67) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318949-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-11-27 | — | — | US | disclosed |
| US-20120014906-A1 | ORGANIC COMPOUNDS | XENON PHARMACEUTICALS INC. (CA) | 2012-01-19 | — | — | US | disclosed |
| US-8049016-B2 | Thiazole derivatives which inhibit stearoyl-CoA desaturase enzymes | NOVARTIS AG (CH) | 2011-11-01 | — | — | US | disclosed |
| CN-102007123-A | Heterocyclic inhibitors of stearoyl-CoA desaturase | NOVARTIS AG | 2011-04-06 | — | — | CN | disclosed |
| US-20090264444-A1 | Organic compounds | XENON PHARMACEUTICALS INC. (CA) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014906-A1 | ORGANIC COMPOUNDS | SCD, SCD5, FADS2 | MAPT 2947/4885ALDH1A1 451/4885MEN1 4876/4885 |
| US-20090264444-A1 | Organic compounds | SCD, SCD5, FADS2 | MAPT 2947/4885ALDH1A1 451/4885MEN1 4876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.