Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | RAB9A | P51151 | 6/20 | 0.77 |
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | DHODH | Q02127 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885791 | 0.87 | MAPT (1.00) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL12158128 | 0.85 | MAPT (0.71) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL1880396 | 0.83 | DHODH (0.69) | MAPTKDM4EALDH1A1HPGDDHODH | |
| SCHEMBL27706920 | 0.83 | RAB9A (0.80) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL4914875 | 0.82 | MAPT (0.69) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL12158131 | 0.80 | MAPT (0.84) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL18320945 | 0.80 | KDM4E (1.00) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL2831045 | 0.79 | L3MBTL1 (0.62) | MAPTKDM4ERAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14223814 | 0.78 | TDP1 (0.61) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL1541108 | 0.77 | MAPT (0.65) | MAPTKDM4EALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8920785-B2 | Cosmetic or dermatological preparations with a content of one or more thiazole derivates | BEIERSDORF AG (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | BEIERSDORF AG (DE) | 2013-02-14 | — | — | US | disclosed |
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | BEIERSDORF AG (DE) | 2013-02-14 | — | — | US | disclosed |
| WO-2011117034-A2 | COSMETIC OR DERMATOLOGICAL PREPARATIONS WITH A CONTENT OF ONE OR MORE THIAZOLE DERIVATIVES | BEIERSDORF AG (DE) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130039870-A1 | Cosmetic Or Dermatological Preparations With A Content Of One Or More Thiazole Derivates | TYR, CUTA, MITF | MAPT 519/4885KDM4E 4197/4885ALDH1A1 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.