Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710041 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL28473229 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Propane SCHEMBL22090164 | 0.84 | — | — | |
| SCHEMBL30341 | 0.83 | — | — | |
| SCHEMBL334659 | 0.83 | — | — | |
| SCHEMBL334658 | 0.83 | — | — | |
| SCHEMBL28100623 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL10530137 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL284231 | 0.82 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| Methane SCHEMBL11336685 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780232-B2 | FOR LENSES; HYDROLYSIS PRODUCT OF A EPOXY-FUNCTIONAL ALKOXYSILANE, AN UNSATURATED MONOMER, AND TO REDUCE THE VISCOSITY, AN UNHYDROLYZED EPOXY-FUNCTIONAL ALKOXYSILANE | THE WALMAN OPTICAL COMPANY | 2004-08-24 | — | — | US | claimed |
| EP-2239301-B1 | SILOXANE RESIN COMPOSITIONS | TORAY INDUSTRIES (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-8389649-B2 | Siloxane-based resin composition | TORAY INDUSTRIES, INC. (JP) | 2013-03-05 | — | — | US | disclosed |
| US-20100316953-A1 | SILOXANE-BASED RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2010-12-16 | — | — | US | disclosed |
| EP-2239301-A1 | SILOXANE RESIN COMPOSITIONS | Toray Industries, Inc. (JP) | 2010-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316953-A1 | SILOXANE-BASED RESIN COMPOSITION | ICAM1, ESD, CAD | SMN1; SMN2 3292/4885ALDH1A1 599/4885TDP1 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.