SCHEMBL3479945

SCHEMBL3479945

CCO[Si](OCC)(OCC)c1cccc2c1ccc1ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.47
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 4/20 0.40
TDP1 Q9NUW8 2/20 0.40
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
LMNA P02545 2/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
APEX1 P27695 1/20 0.38
MAPK1 P28482 1/20 0.38
PMP22 Q01453 1/20 0.38
HPGD P15428 4/20 0.36
KDM4E B2RXH2 1/20 0.36
PAX8 Q06710 1/20 0.36
CYP1A2 P05177 2/20 0.35
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35
THRB P10828 1/20 0.35
CDC25B P30305 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777494 1.00 HPRT1 (0.47) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL106903 0.90 HPGD (0.40) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL29859741 0.90 HPGD (0.40) ALDH1A1HSD17B10TDP1CYP2A6TSHR
Potassium SCHEMBL6411447 0.88 HPGD (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL6409390 0.88 HPGD (0.39) ALDH1A1HSD17B10TDP1CYP2A6TSHR
SCHEMBL2553647 0.87 HPRT1 (0.44) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL15848163 0.84 HPRT1 (0.44) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL1929080 0.83 TRPM4 (0.38) HPRT1ALDH1A1HSD17B10TDP1CYP2A6
SCHEMBL20466120 0.82 GABRP (0.35) ALDH1A1TSHRMAPTMAPK1HPGD
SCHEMBL15848345 0.81 HPRT1 (0.41) HPRT1ALDH1A1HSD17B10TDP1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109081921-B Silicon-based hard mask 罗门哈斯电子材料有限责任公司 2021-07-06 CN disclosed
CN-107076894-B Infrared shielding composition, cured film, and solid-state imaging device JSR株式会社 2020-01-31 CN disclosed
EP-2914664-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO LTD (JP) 2016-09-07 EP disclosed
EP-2239301-B1 SILOXANE RESIN COMPOSITIONS TORAY INDUSTRIES (JP) 2016-04-27 EP disclosed
US-9312196-B2 Curable silicone composition, cured product thereof, and optical semiconductor DOW CORNING TORAY CO., LTD. (JP) 2016-04-12 US disclosed
US-20150252221-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor DOW TORAY CO., LTD. (JP) 2015-09-10 US disclosed
EP-2914664-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2015-09-09 EP disclosed
WO-2014069610-A1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-05-08 WO disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD HPRT1 2773/4885ALDH1A1 599/4885HSD17B10 1203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.