Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13022868 | 0.90 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL3480267 | 0.89 | — | — | |
| SCHEMBL13024347 | 0.88 | TRPV4 (0.32) | PTGDRPTGDR2TRPV4 | |
| SCHEMBL13021133 | 0.88 | PTGDR (0.31) | PTGDRPTGDR2TRPV4 | |
| SCHEMBL13022839 | 0.86 | PTGDR (0.32) | PTGDRPTGDR2TRPV4 | |
| SCHEMBL3480356 | 0.86 | TRPV4 (0.33) | PTGDRPTGDR2TRPV4 | |
| SCHEMBL13032049 | 0.84 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL13032069 | 0.84 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14943031 | 0.83 | TRPV4 (0.34) | TRPV4 | |
| SCHEMBL3480146 | 0.81 | PTGDR (0.32) | PTGDRPTGDR2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | claimed |
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MGAM, BPGM, PPME1 | PTGDR 3286/4885PTGDR2 4042/4885TRPV4 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.