Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5569327 | 0.79 | FAAH (0.51) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL11372041 | 0.71 | FAAH (0.64) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL3862615 | 0.70 | TSHR (0.42) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL10750032 | 0.68 | FAAH (0.51) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL28176966 | 0.68 | FAAH (0.48) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL2820218 | 0.67 | TSHR (0.39) | FAAHNAAARAB9ATSHRPOLB | |
| SCHEMBL11370007 | 0.66 | NAAA (0.77) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL14618053 | 0.65 | FAAH (0.51) | FAAHNAAANPC1RAB9ATSHR | |
| SCHEMBL16424936 | 0.65 | TSHR (0.49) | RAB9ATSHRPOLBALDH1A1MAPT | |
| SCHEMBL9168611 | 0.65 | TSHR (0.42) | FAAHNAAANPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147042-A1 | DENDRITIC MOLECULES | The University Of Queensland (AU) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008141357-A1 | DENDRITIC MOLECULES | THE UNIVERSITY OF QUEENSLAND (AU) | 2008-11-27 | — | — | WO | disclosed |