Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795329 | 0.84 | ALDH1A1 (0.62) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL10468140 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL10470167 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL6793786 | 0.81 | CYP1A2 (0.70) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL7697964 | 0.79 | KDM4E (0.68) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL10469448 | 0.79 | ALDH1A1 (0.60) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL1432938 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL7694742 | 0.77 | KDM4E (0.73) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL6794207 | 0.76 | KDM4E (0.68) | ALDH1A1KDM4ECYP1A2CYP2C9POLB | |
| SCHEMBL978291 | 0.76 | KDM4E (0.71) | ALDH1A1KDM4ECYP1A2CYP2C9POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | claimed |
| US-20100056794-A1 | PROCESS FOR THE PREPARATION OF 2,5-BIS-(2,2,2-TRIFLUOROETHOXY)-N-(2-PIPERIDYL-METHYL)-BENZAMIDE AND SALTS THEREOF | GRINDEKS A JOINT STOCK COMPANY (LV) | 2010-03-04 | — | — | US | disclosed |
| EP-1918280-A1 | Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof | "Joint Stock Company Grindeks" (LV) | 2008-05-07 | — | — | EP | disclosed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056794-A1 | PROCESS FOR THE PREPARATION OF 2,5-BIS-(2,2,2-TRIFLUOROETHOXY)-N-(2-PIPERIDYL-METHYL)-BENZAMIDE AND SALTS THEREOF | BOLA2; BOLA2B, TET2, CYP1A2 | ALDH1A1 430/4885KDM4E 429/4885CYP1A2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.