Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795329 | 0.86 | ALDH1A1 (0.62) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL1098123 | 0.86 | CYP2C9 (0.73) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL7697964 | 0.84 | KDM4E (0.68) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL1432938 | 0.82 | ALDH1A1 (0.72) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL7694742 | 0.82 | KDM4E (0.73) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL978291 | 0.81 | KDM4E (0.71) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL3480480 | 0.81 | ALDH1A1 (0.66) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL5485870 | 0.80 | KDM4E (1.00) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL14622160 | 0.80 | ALDH1A1 (0.68) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB | |
| SCHEMBL11784892 | 0.80 | KDM4E (0.79) | CYP1A2CYP2C9ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | MCDANIEL WILLIAM C | 2004-11-04 | — | — | US | claimed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | claimed |
| US-20040220409-A1 | Flecainide synthesis | MCDANIEL WILLIAM C | 2004-11-04 | — | — | US | disclosed |
| WO-2002066413-A1 | FLECAINIDE SYNTHESIS | NARCHEM CORPORATION (US) | 2002-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040220409-A1 | Flecainide synthesis | KCNH1, CYP3A43, CYP2F1 | CYP1A2 49/4885CYP2C9 27/4885ALDH1A1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.