Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.50 |
| ▸ | NOS2 | P35228 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27999937 | 0.88 | NOS2 (0.47) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL15357992 | 0.87 | AR (0.44) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL8608813 | 0.78 | AR (0.58) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6229277 | 0.77 | MAOA (0.46) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30122081 | 0.77 | MAOA (0.46) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6230783 | 0.75 | AR (0.47) | ARMAOAMAOBKDM4EMAPT | |
| SCHEMBL22804940 | 0.74 | MAOB (0.58) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL1017624 | 0.74 | KDM4E (0.45) | ARNOS2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL3480893 | 0.73 | KDM4E (0.54) | ARMAOAMAOBKDM4EMAPT | |
| SCHEMBL17080256 | 0.72 | MAOB (0.63) | ARCYP2D6MAOAMAOBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767626-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7612105-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1076053-B1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-7037930-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6858639-B2 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-04-10 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1076053-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | AR 419/4885NOS2 1397/4885CYP2D6 60/4885 |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | CYP1B1, CYP2B6, CBR3 | AR 537/4885NOS2 2305/4885CYP2D6 34/4885 |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | CBR3, MSRB3, CYP1B1 | AR 419/4885NOS2 1397/4885CYP2D6 60/4885 |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | AR 419/4885NOS2 1397/4885CYP2D6 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.