Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961607 | 0.81 | AKR1C3 (0.37) | PTGESCYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL3480476 | 0.79 | PTGES (0.53) | PTGESCYP3A4TSHRTDP1APP | |
| SCHEMBL5961611 | 0.78 | PTGES (0.40) | PTGESTHRBCYP3A4MAPK1TSHR | |
| SCHEMBL5961616 | 0.74 | PTGES (0.43) | PTGESCYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL5961613 | 0.74 | PTGES (0.41) | PTGESCYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL3480631 | 0.71 | PTGES (0.36) | PTGESCYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL9586989 | 0.71 | THRB (0.52) | THRBCYP3A4MAPK1TSHRTDP1 | |
| SCHEMBL1136130 | 0.70 | PDE7A (0.51) | MAPK1TDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4596243 | 0.68 | GSTP1 (0.53) | THRBCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL1192787 | 0.68 | MAPT (0.44) | CYP3A4MAPK1TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767626-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7612105-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1076053-B1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-7037930-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6858639-B2 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-04-10 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1076053-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | PTGES 1990/4885THRB 768/4885CYP3A4 15/4885 |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | CYP1B1, CYP2B6, CBR3 | PTGES 2703/4885THRB 1024/4885CYP3A4 22/4885 |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | CBR3, MSRB3, CYP1B1 | PTGES 1990/4885THRB 768/4885CYP3A4 15/4885 |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | PTGES 1990/4885THRB 768/4885CYP3A4 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.