⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480685 | 0.81 | — | — | |
| SCHEMBL19733115 | 0.79 | — | — | |
| SCHEMBL21065773 | 0.74 | — | — | |
| SCHEMBL6857940 | 0.73 | TSHR (0.35) | — | |
| SCHEMBL4188648 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL5950138 | 0.71 | — | — | |
| SCHEMBL3840454 | 0.71 | — | — | |
| SCHEMBL17799148 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL22734159 | 0.69 | TSHR (0.42) | — | |
| SCHEMBL22116235 | 0.69 | DNM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962745-B2 | Functionalized polymers and vulcanizates with reduced hysteretic loss | BRIDGESTONE CORPORATION (JP) | 2015-02-24 | — | — | US | claimed |
| JP-2010530464-A | — | — | 2010-09-09 | — | — | JP | claimed |
| EP-2160414-A2 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | Bridgestone Corporation (JP) | 2010-03-10 | — | — | EP | claimed |
| WO-2008156788-A2 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORPORATION (JP) | 2008-12-24 | — | — | WO | claimed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | claimed |
| US-20220403057-A1 | RUBBER COMPOSITION AND TIRE | BRIDGESTONE CORPORATION (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-2160414-B1 | POLYMERS FUNCTIONALIZED WITH HALOSILANES CONTAINING AN AMINO GROUP | BRIDGESTONE CORP (JP) | 2017-05-10 | — | — | EP | disclosed |