Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480927 | 0.81 | TRPA1 (0.30) | — | |
| SCHEMBL3480624 | 0.80 | EGLN1 (0.31) | ALDH1A1EGLN1 | |
| SCHEMBL3480587 | 0.79 | PDK2 (0.49) | CFTRNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3480631 | 0.78 | PTGES (0.36) | RAB9ASMN1; SMN2LMNAMAPTNPSR1 | |
| SCHEMBL3906252 | 0.68 | CFTR (0.43) | CFTRNPC1LMNAHTTMAPT | |
| SCHEMBL3480813 | 0.68 | CFTR (0.34) | CFTRPOLBHSD17B10CA2 | |
| SCHEMBL19628568 | 0.67 | RET (0.36) | — | |
| SCHEMBL10144072 | 0.66 | HSD17B10 (0.67) | CFTRNPC1RAB9APOLBHSD17B10 | |
| SCHEMBL8618607 | 0.66 | KDM4E (0.44) | CFTRNPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL3480515 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767626-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7612105-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-11-03 | — | — | US | disclosed |
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-07-02 | — | — | US | disclosed |
| EP-1076053-B1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-7037930-B2 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-05-19 | — | — | US | disclosed |
| US-6858639-B2 | 3-Arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-04-10 | — | — | US | disclosed |
| US-6509354-B1 | Insecticides and miticides containing the 3-arylphenyl sulfide derivatives as an active ingredient. | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1076053-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVES AND INSECTICIDES AND MITICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170883-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | CFTR 398/4885ALPL 4253/4885NPC1 2264/4885 |
| US-20030069242-A1 | 3-arylphenyl sulfide derivative and insecticide and miticide | CYP1B1, CYP2B6, CBR3 | CFTR 180/4885ALPL 4289/4885NPC1 1795/4885 |
| US-20050171097-A1 | 3-Arylphenyl sulfide derivative and insecticide and miticide | CBR3, MSRB3, CYP1B1 | CFTR 398/4885ALPL 4253/4885NPC1 2264/4885 |
| US-20050107383-A1 | 3-ARYLPHENYL SULFIDE DERIVATIVE AND INSECTICIDE AND MITICIDE | CBR3, MSRB3, CYP1B1 | CFTR 398/4885ALPL 4253/4885NPC1 2264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.