Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.42 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894649 | 0.92 | SPHK1 (0.42) | SPHK1SPHK2ESR2DRD2 | |
| SCHEMBL10895877 | 0.82 | SPHK1 (0.56) | SPHK1SPHK2DRD2 | |
| SCHEMBL11066946 | 0.82 | SPHK1 (0.56) | SPHK1SPHK2DRD2 | |
| SCHEMBL21398391 | 0.82 | SPHK1 (0.56) | SPHK1SPHK2ESR2 | |
| SCHEMBL8038554 | 0.80 | DRD2 (0.39) | ESR2DRD2 | |
| SCHEMBL2384867 | 0.79 | CYP2C9 (0.42) | SPHK1SPHK2ESR2 | |
| SCHEMBL3480904 | 0.79 | SPHK1 (0.47) | SPHK1SPHK2ESR2 | |
| SCHEMBL14403054 | 0.77 | ESR2 (0.44) | ESR2DRD2 | |
| SCHEMBL4323763 | 0.77 | SPHK1 (0.61) | SPHK1SPHK2DRD2 | |
| SCHEMBL8731338 | 0.77 | GRIA1 (0.38) | ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8273264-B2 | Liquid-crystal compounds and LC media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-09-25 | — | — | US | disclosed |
| EP-2208775-B1 | Liquid crystalline compound and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2208775-B1 | Liquid crystalline compound and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-07-25 | — | — | EP | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| EP-2208775-A1 | Liquid crystal compounds and FK media | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
| EP-2208775-A1 | Liquid crystal compounds and FK media | Merck Patent GmbH (DE) | 2010-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100181533-A1 | Liquid-crystal compounds and LC media | VCL, LCT, NEFM | SPHK1 1137/4885SPHK2 1549/4885ESR2 3177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.