Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.30 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.30 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11017137 | 0.86 | CDK2 (0.38) | TTRAPEX1AURKAAURKBTDP1 | |
| SCHEMBL3708176 | 0.83 | MYC (0.36) | TTRAPEX1CYP1A2HSD17B10TSHR | |
| SCHEMBL8075768 | 0.81 | TTR (0.39) | TTRAPEX1HSD17B10TSHRALDH1A1 | |
| SCHEMBL14495128 | 0.81 | MYC (0.36) | TTRAPEX1CYP1A2HSD17B10TSHR | |
| SCHEMBL10645525 | 0.80 | TTR (0.35) | TTRAPEX1AURKAAURKBCYP1A2 | |
| SCHEMBL1170678 | 0.80 | KYNU (0.47) | TTRAPEX1HSD17B10ALDH1A1 | |
| SCHEMBL599747 | 0.78 | TTR (0.59) | TTRAPEX1AURKAAURKBCYP1A2 | |
| SCHEMBL9178147 | 0.78 | TTR (0.58) | TTRAPEX1HSD17B10TSHRALDH1A1 | |
| SCHEMBL9335165 | 0.77 | CA2 (0.39) | AURKAAURKBHSD17B10ALDH1A1THRB | |
| SCHEMBL7624190 | 0.77 | PLAU (0.43) | TTRAPEX1HSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7708786-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2010-05-04 | — | — | US | disclosed |
| US-20090025152-A1 | DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND USE | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2009-01-29 | — | — | US | disclosed |
| US-7455699-B2 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-11-25 | — | — | US | disclosed |
| US-20050166339-A1 | Dye mixtures of fiber-reactive azo dyes, their preparation and use | DYSTAR TEXTILFARBEN GMBH & CO.DEUTSCHLAND KG (DE) | 2005-08-04 | — | — | US | disclosed |