SCHEMBL348193

SCHEMBL348193

NCCCNCCCCNCCC(Cl)(Cl)N(Cl)Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.52
CA6 P23280 4/20 0.52
CA7 P43166 4/20 0.52
CA9 Q16790 4/20 0.52
CA14 Q9ULX7 4/20 0.52
CA5B Q9Y2D0 4/20 0.52
CA2 P00918 3/20 0.52
CA4 P22748 3/20 0.52
CA5A P35218 3/20 0.52
ALOX15 P16050 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
F13A1 P00488 2/20 0.52
CYP1A2 P05177 2/20 0.52
THPO P40225 2/20 0.52
CASP2 P42575 2/20 0.52
RECQL P46063 2/20 0.52
CYP2C19 P33261 1/20 0.52
HSD17B10 Q99714 1/20 0.52
CA3 P07451 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18825662 0.96 CA12 (0.50) CA12CA6CA7CA9CA14
Spermine SCHEMBL27722730 0.75 CA12 (0.81) CA12CA6CA7CA9CA14
SCHEMBL9834009 0.72 CA12 (0.52) CA12CA6CA7CA9CA14
Spermine SCHEMBL4189337 0.72 CA12 (0.87) CA12CA6CA7CA9CA14
Spermine SCHEMBL30446193 0.72 CA12 (1.00) CA12CA6CA7CA9CA14
SCHEMBL26132507 0.72 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL288720 0.72 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL14965 0.72 CA12 (1.00) CA12CA6CA7CA9CA14
Spermine SCHEMBL8514287 0.72 CA12 (1.00) CA12CA6CA7CA9CA14
Hydrochloric Acid SCHEMBL28862282 0.71 LMNA (0.58) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003055890-A1 THIENOPYRIMIDINE DERIVATIVE COMPOUNDS AS INHIBITORS OF PROLYLPEPTIDASE, INDUCERS OF APOPTOSIS AND CANCER TREATMENT AGENTS BAYER PHARMACEUTICALS CORPORATION (US) 2003-07-10 WO claimed
WO-2003055489-A1 2,4-DIAMINO-PYRIMIDINE DERIVATIVE COMPOUNDS AS INHIBITORS OF PROLYLPEPTIDASE, INDUCERS OF APOPTOSIS AND CANCER TREATMENT AGENTS BAYER PHARMACEUTICALS CORPORATION (US) 2003-07-10 WO claimed
WO-2003055866-A1 QUINAZOLINE AND QUINOLINE DERIVATIVE COMPOUNDS AS INHIBITORS OF PROLYLPEPTIDASE, INDUCERS OF APOPTOSIS AND CANCER TREATMENT AGENTS BAYER PHARMACEUTICALS CORPORATION (US) 2003-07-10 WO claimed
US-20250000942-A1 PEPTIDES AND METHODS OF TRANSPLANTATION AND RESTORATIVE ORGAN FUNCTION PRINCE BIOTECH, LLC 2025-01-02 US disclosed
CN-118980553-A Size-based separation of dissociated fixed tissue 文塔纳医疗系统公司 2024-11-19 CN disclosed
CN-110520735-B Size-based separation of dissociated fixed tissue 文塔纳医疗系统公司 2024-07-09 CN disclosed
US-20240210288-A1 Representative Diagnostics VENTANA MED SYST INC (US) 2024-06-27 US disclosed
US-11959838-B2 Representative diagnostics VENTANA MEDICAL SYSTEMS, INC. (US) 2024-04-16 US disclosed
US-20240077391-A1 SIZE-BASED SEPARATION OF DISSOCIATED FIXED TISSUES VENTANA MED SYST INC (US) 2024-03-07 US disclosed
US-11768137-B2 Size-based separation of dissociated fixed tissues VENTANA MEDICAL SYSTEMS, INC. (US) 2023-09-26 US disclosed
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF UNIV MARYLAND (US) 2023-04-27 US disclosed
US-6294136-B1 SYSTEM COMPRISING SINGLE NUCLEIC ACID MOLECULE ELONGATED AND FIXED ALONG ITS LENGTH ONTO SOLID PLANAR SURFACE TO BE INDIVIDUALLY ANALYZABLE AND ACCESSIBLE FOR ENZYMATIC AND/OR HYBRIDIZATION REACTIONS, IMAGING DEVICE WISCONSIN ALUMNI RESEARCH FOUNDATION 2001-09-25 US disclosed
EP-1058562-A1 COMPOSITIONS AND METHODS OF TREATING TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2000-12-13 EP disclosed
US-6147198-A NUCLEOTIDE SEQUENCES ELONGATED AND FIXED LENGTHWISE ON A SURFACE; FOR USE AS DIAGNOSTIC TOOLS DURING SEQUENCING AND GENOME ANALYSIS NEW YORK UNIVERSITY (US) 2000-11-14 US disclosed
WO-1999044645-A1 COMPOSITIONS AND METHODS OF TREATING TUMORS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1999-09-10 WO disclosed
EP-0871640-A1 METHODS FOR MEASURING PHYSICAL CHARACTERISTICS OF NUCLEIC ACIDS BY MICROSCOPIC IMAGING NEW YORK UNIVERSITY (US) 1998-10-21 EP disclosed
US-5720928-A Image processing and analysis of individual nucleic acid molecules NEW YORK UNIVERSITY (US) 1998-02-24 US disclosed
WO-1997031107-A2 HUMAN SERUM LECTIN - INDUCED APOPTOSIS AND METHOD FOR DETECTING APOPTOSIS COLES JOHN G (CA) 1997-08-28 WO disclosed
WO-1997011691-A1 TREATMENT OF HUMAN PROSTATE CANCER WITH SPERMINE CHILDREN'S MEDICAL CENTER CORPORATION (US) 1997-04-03 WO disclosed
WO-1996031522-A1 METHODS FOR MEASURING PHYSICAL CHARACTERISTICS OF NUCLEIC ACIDS BY MICROSCOPIC IMAGING NEW YORK UNIVERSITY (US) 1996-10-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230125630-A1 POLYPHOSPHAZENES, METHODS OF MAKING, AND USES THEREOF PHOSPHO1, PLCG2, PLCG1 CA12 154/4885CA6 413/4885CA7 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.