Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268449 | 0.89 | MEN1 (0.44) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3482670 | 0.85 | MEN1 (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11588974 | 0.84 | KMT2A (0.52) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL7271033 | 0.84 | KMT2A (0.52) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL13774925 | 0.81 | KMT2A (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL1697372 | 0.80 | ALDH1A1 (0.48) | KMT2ASMN1; SMN2LMNATSHRMAPT | |
| SCHEMBL8915981 | 0.79 | HTT (0.50) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL567578 | 0.78 | MEN1 (0.56) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10887763 | 0.78 | MEN1 (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL15552484 | 0.77 | KMT2A (0.55) | MEN1KMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107993-A2 | PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE | PLIVA HRVATSKA D.O.O. (HR) | 2010-09-23 | — | — | WO | claimed |
| WO-2010107993-A2 | PROCESS FOR PREPARING (R)-7V-BENZYL-2- (BENYLOXYCARBONYLAMINO)-S-METHOXYPROPIONAMIDE | PLIVA HRVATSKA D.O.O. (HR) | 2010-09-23 | — | — | WO | disclosed |