Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27298902 | 0.84 | CYP2D6 (0.46) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL1162490 | 0.84 | ALDH1A1 (0.48) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL3482896 | 0.80 | MEN1 (0.47) | ALDH1A1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL3458059 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL17451141 | 0.76 | ALDH1A1 (0.49) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL21758221 | 0.76 | ALDH1A1 (0.49) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL4406979 | 0.76 | ALDH1A1 (0.38) | ALDH1A1RECQLMMP8CYP2C9CYP2C19 | |
| SCHEMBL13071451 | 0.74 | RIPK1 (0.45) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL21621500 | 0.73 | LMNA (0.48) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 | |
| SCHEMBL332422 | 0.73 | LMNA (0.48) | ALDH1A1RECQLMMP8CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |