SCHEMBL3482898

SCHEMBL3482898

C[Si](C)(c1ccc(C(=O)O)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 1.00
TSHR P16473 3/20 0.60
TP53 P04637 1/20 0.60
ALDH1A1 P00352 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SRD5A2 P31213 4/20 0.52
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA12 O43570 1/20 0.50
CA3 P07451 1/20 0.50
TYR P14679 1/20 0.50
DRD1 P21728 1/20 0.50
CA4 P22748 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
ESR1 P03372 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105892 0.85 HPGD (0.74) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL1930618 0.83 HPGD (0.71) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL30910037 0.81 HPGD (0.68) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL2786186 0.79 HPGD (0.65) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL16749651 0.79 TSHR (0.67) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL8413865 0.78 HPGD (0.64) HPGDTSHRTP53ALDH1A1SMN1; SMN2
Terephthalic Acid SCHEMBL11416580 0.78 TSHR (0.86) HPGDTSHRTP53ALDH1A1SMN1; SMN2
Terephthalic Acid SCHEMBL1403607 0.78 TSHR (0.86) HPGDTSHRTP53ALDH1A1SMN1; SMN2
Terephthalic Acid SCHEMBL1403625 0.78 TSHR (0.86) HPGDTSHRTP53ALDH1A1SMN1; SMN2
SCHEMBL14065860 0.78 HPGD (0.63) HPGDTSHRTP53ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116003927-B Butyl rubber capable of being repeatedly processed and preparation method thereof 山东泰瑞丰新材料有限公司 2023-08-01 CN claimed
CN-116003927-A Butyl rubber capable of being repeatedly processed and preparation method thereof 山东泰瑞丰新材料有限公司 2023-04-25 CN claimed
CN-113227207-A Polyamic acid composition and transparent polyimide film using same 株式会社斗山 2021-08-06 CN claimed
CN-109897180-A Polyamic acid solution, clear polyimides resin film and transparent substrate using it 株式会社斗山 2019-06-18 CN claimed
EP-3088440-B1 TRANSPARENT POLYAMIDE-IMIDE RESIN AND FILM USING SAME KOLON INC (KR) 2018-09-19 EP claimed
US-4940810-A OXIDATION OF DIALKYLDIARYLSILANE AMOCO CORPORATION (US) 1990-07-10 US claimed
US-12630470-B2 Polyamideimide film and window cover film including the same SK INNOVATION CO., LTD. (KR) 2026-05-19 US disclosed
WO-2026100662-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2026-05-15 WO disclosed
US-12607780-B2 Display device LG DISPLAY CO., LTD. (KR) 2026-04-21 US disclosed
US-20250348000-A1 RESIST UNDERLAYER FILM-FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-11-13 US disclosed
CN-114058044-B Polyimide base film and flexible display panel comprising same SK新技术株式会社 2025-06-24 CN disclosed
US-20250155813-A1 PROTECTIVE FILM FORMING COMPOSITION NISSAN CHEMICAL CORPORATION (JP) 2025-05-15 US disclosed
WO-2025033304-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL ALIGNMENT FILM, AND METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-02-13 WO disclosed
US-4175178-A NONFLAMMABLE FILMS AND FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4175180-A FILMS OR FILAMENTS, NONFLAMMABLE S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4172935-A FILMS, FILAMENTS S.A TEXACO BELGIUM N.V. (BE) 1979-10-30 US disclosed
US-4165424-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-08-21 US disclosed
US-4147711-A Ethylenic silicon compounds and thermoplastic elastomers obtained therefrom RHONE-POULENC INDUSTRIES (FR) 1979-04-03 US disclosed
US-4098768-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1978-07-04 US disclosed
US-4088670-A P-(DIMETHYLVINYLSILYL-METHOXY)-BENZOYL CHLORIDE FROM DIMETHYLVINYL-CHLOROMETHYLSILANE AND A P-HYDROXYBENZOIC ACID RHONE-POULENC INDUSTRIES (FR) 1978-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630470-B2 Polyamideimide film and window cover film including the same DDT, B2M, ATG13 HPGD 4726/4885TSHR 476/4885TP53 2138/4885
US-12607780-B2 Display device ECPAS, RICTOR, FAP HPGD 4431/4885TSHR 3431/4885TP53 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.