Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.67 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | CASP1 | P29466 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LATS1 | O95835 | 1/20 | 0.43 |
| ▸ | GAK | O14976 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15328263 | 0.89 | PDGFRB (0.54) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL1304390 | 0.89 | PDGFRB (0.51) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL348350 | 0.85 | CYP1A2 (0.47) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL346309 | 0.85 | PDGFRB (0.50) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL15533402 | 0.85 | ALDH1A1 (0.48) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL23068690 | 0.82 | CYP1A2 (0.54) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL15327931 | 0.82 | ALDH1A1 (0.44) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL347611 | 0.82 | ALDH1A1 (0.44) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL30749413 | 0.81 | PDGFRB (0.49) | PDGFRBPDGFRAKDM4EMAPTKMT2A | |
| SCHEMBL15328004 | 0.80 | ABCG2 (0.45) | PDGFRBPDGFRAKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889698-B2 | Compounds for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2014-11-18 | — | — | US | disclosed |
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | RESVERLOGIX CORP. | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015905-A1 | COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | APOB, HDLBP, FABP3 | PDGFRB 2890/4885PDGFRA 3065/4885KDM4E 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.