SCHEMBL34837

SCHEMBL34837

CS(=O)(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.61
CA1 P00915 3/20 0.61
CA12 O43570 3/20 0.61
CA9 Q16790 3/20 0.61
CA14 Q9ULX7 2/20 0.61
CA3 P07451 1/20 0.61
CA6 P23280 1/20 0.61
CYP2C19 P33261 1/20 0.61
CA5A P35218 1/20 0.61
CA7 P43166 1/20 0.61
CA5B Q9Y2D0 1/20 0.61
TP53 P04637 1/20 0.57
TSHR P16473 1/20 0.57
AKR1C3 P42330 2/20 0.56
ENPP2 Q13822 1/20 0.56
ALDH1A1 P00352 2/20 0.55
KMT2A Q03164 1/20 0.55
PTGS2 P35354 1/20 0.55
F2 P00734 2/20 0.53
PRSS1 P07477 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11213950 0.98 CA2 (0.59) CA2CA1CA12CA9CA14
SCHEMBL2349058 0.94 CA12 (0.66) CA2CA1CA12CA9CA14
SCHEMBL29035638 0.90 CA12 (0.52) CA2CA1CA12CA9CA14
SCHEMBL5464915 0.88 CA1 (0.50) CA2CA1CA12CA9CA14
Pyrrole SCHEMBL29202626 0.87 PTGS2 (0.49) CA2CA1CA12CA9CA14
SCHEMBL1834055 0.84 CA12 (0.71) CA2CA1CA12CA9ALDH1A1
SCHEMBL11732738 0.84 CA1 (0.60) CA2CA1CA12CA9KMT2A
SCHEMBL7619212 0.84 SRD5A2 (0.56) CA2CA1CA12CA9CA14
SCHEMBL29182525 0.84 AKR1C3 (0.47) CA2CA1CA12CA9CA14
SCHEMBL21165691 0.83 TSHR (0.60) CA2CA1CA12CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-119859148-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2025-04-22 CN claimed
CN-118666721-A Synthesis method of mesotrione 台州市博联贵金属有限公司 2024-09-20 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117926366-A High-strength titanium alloy luggage rack and preparation process thereof 扬州元辰汽车配件有限公司 2024-04-26 CN claimed
CN-109760944-B Liquid sealing method of o-nitro-p-methylsulfonyl benzoic acid production matched device 浙江嘉福新材料科技有限公司 2024-03-29 CN claimed
CN-113493401-B Preparation method of p-methylsulfonylbenzoic acid 潍坊润谱化学有限公司 2023-03-03 CN claimed
CN-111978201-B Synthesis method of N, N' -diaryl benzoyl hydrazine compound 甘肃农业大学 2023-01-03 CN claimed
CN-115304523-A Synthetic method of 3-methyl-2-chloro-4-methylsulfonylbenzoic acid 帕潘纳(北京)科技有限公司 2022-11-08 CN claimed
EP-3237562-A1 USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT AND/OR COBALT ALLOY COMPRISING SUBSTRATES BASF SE (DE) 2017-11-01 EP claimed
WO-2016102531-A1 USE OF A CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION FOR POLISHING OF COBALT AND/OR COBALT ALLOY COMPRISING SUBSTRATES BASF SE (DE) 2016-06-30 WO claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
EP-1851201-A1 1-{4-[(1-CYCLOBUTYL-4-PIPERIDINYL)OXY]PHENYL}-4-{[4-(METHYLSULFONYL)PHENYL]CARBONYL}PIPERAZINE AS HISTAMINE H3 ANTAGONIST GLAXO GROUP LIMITED (GB) 2007-11-07 EP claimed
WO-2006090142-A9 l-{4- [ (l-CYCLOBUTYL-4-PIPERIDINYL) OXY] PHENYL] -4-{ [4- (METHYLSULFONYL) PHENYL]CARBONYL PIPERAZINE AS HISTAMINE H3 ANTAGONIST GLAXO GROUP LTD (GB) 2006-11-02 WO claimed
WO-2006090142-A1 l-{4- [ (l-CYCLOBUTYL-4-PIPERIDINYL) OXY] PHENYL] -4-{ [4- (METHYLSULFONYL) PHENYL]CARBONYL PIPERAZINE AS HISTAMINE H3 ANTAGONIST GLAXO GROUP LIMITED (GB) 2006-08-31 WO claimed
US-20060019964-A1 Antiallergens; antiinflammatory agents; rhinitis; serotonin receptor antagonist GLAXO GROUP LIMITED (GB) 2006-01-26 US claimed
US-4758312-A Adding colorless electrochemically active compound having positive reduction potential NALCO CHEMICAL COMPANY (US) 1988-07-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CA2 3509/4885CA1 4047/4885CA12 4479/4885
US-20060019964-A1 Antiallergens; antiinflammatory agents; rhinitis; serotonin receptor antagonist HRH2, HRH4, HRH1 CA2 3514/4885CA1 4690/4885CA12 4774/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS CA2 3509/4885CA1 4047/4885CA12 4479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.