SCHEMBL3484459

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3484456	1.00	P4HB (0.56)	P4HBTHRBHTTLMNASMN1; SMN2
	SCHEMBL3484504	0.92	P4HB (0.57)	P4HBTHRBHTTLMNASMN1; SMN2
	SCHEMBL3484500	0.92	P4HB (0.57)	P4HBTHRBHTTLMNASMN1; SMN2
	SCHEMBL3484188	0.92	LMNA (0.55)	P4HBHTTLMNASMN1; SMN2NPSR1
	SCHEMBL3484185	0.92	LMNA (0.55)	P4HBHTTLMNASMN1; SMN2NPSR1
	SCHEMBL3483949	0.89	P4HB (0.69)	P4HBLMNASMN1; SMN2NPSR1
	SCHEMBL3483951	0.89	P4HB (0.69)	P4HBLMNASMN1; SMN2NPSR1
	SCHEMBL30384818	0.89	P4HB (0.69)	P4HBLMNASMN1; SMN2NPSR1
	SCHEMBL3484321	0.89	XDH (0.54)	P4HBLMNANPSR1
	SCHEMBL3484319	0.89	XDH (0.54)	P4HBLMNANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.