Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 3/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3484841 | 0.89 | NR1H4 (0.40) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL8236165 | 0.84 | CYP4A11 (0.45) | SLC7A5CA1CA2CYP4A11CYP4F2 | |
| SCHEMBL3485088 | 0.83 | SLC7A5 (0.40) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL3484851 | 0.79 | RARB (0.42) | RXRAADRB1ADRB3NR1H4 | |
| SCHEMBL3016468 | 0.74 | CYP4A11 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL3484856 | 0.74 | NR1H4 (0.41) | RXRAADRB1ADRB3NR1H4 | |
| SCHEMBL8242478 | 0.74 | CYP4A11 (0.44) | SLC7A5CA1CA2CYP4A11CYP4F2 | |
| SCHEMBL14213080 | 0.73 | FFAR4 (0.43) | SLC7A5CA12CA1CA14RXRA | |
| SCHEMBL3485094 | 0.72 | NR1H4 (0.41) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL14011593 | 0.72 | CYP4A11 (0.47) | SLC7A5CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8609727-B2 | Dicarboxylic acid derivatives and their use | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-12-17 | — | — | US | disclosed |
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029772-A1 | Dicarboxylic Acid Derivatives and their Use | PC, SLC25A1, GOT2 | SLC7A5 896/4885CA12 1185/4885CA1 1123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.