Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38870 | 0.89 | ALDH1A1 (0.44) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL29439072 | 0.89 | ALDH1A1 (0.44) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL29521196 | 0.82 | KMT2A (0.68) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL1275568 | 0.82 | KMT2A (0.68) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL15881404 | 0.81 | ALDH1A1 (0.38) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| Succinimide SCHEMBL28533922 | 0.79 | ALDH1A1 (0.36) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL16428359 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL10905515 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL29936283 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1TDP1KDM4EALDH1A1 | |
| SCHEMBL5352784 | 0.78 | ALDH1A1 (0.36) | KMT2AMEN1TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | disclosed |