Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29439072 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL38870 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| Succinimide SCHEMBL28533922 | 0.84 | ALDH1A1 (0.36) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL136158 | 0.80 | KDM4E (0.34) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL15881404 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL3485158 | 0.78 | KMT2A (0.49) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL16428359 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| Pyrene SCHEMBL5502107 | 0.77 | KMT2A (0.46) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL10905515 | 0.76 | ALDH1A1 (0.43) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL5349813 | 0.76 | AKR1C3 (0.35) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11121176-B2 | Nearly 2D electronic microparticles | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-09-14 | — | — | US | disclosed |
| US-20130183249-A1 | Stimulus Sensitive Magnetic Nanocomposite Using Pyrene Polymer, and Contrast Medium Composition Containing the Nanocomposite | INDUSTRY ACADEMIC COOPERATION FOUNDATION YOUNSEI UNIVERSITY (KR) | 2013-07-18 | — | — | US | disclosed |
| US-7235650-B2 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-7223833-B1 | Peptide nucleic acid conjugates | ISIS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7125975-B2 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| US-7122649-B2 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050158727-A1 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. | 2005-07-21 | — | — | US | disclosed |
| US-6919439-B2 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20050043219-A1 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. | 2005-02-24 | — | — | US | disclosed |
| US-6831166-B2 | Nucleoside composition for use as tool in human therapeutics and diagnositcs | ISIS PHARMACEUTICALS, INC. | 2004-12-14 | — | — | US | disclosed |
| EP-0724447-B1 | DERIVATIZED OLIGONUCLEOTIDES HAVING IMPROVED UPTAKE | ISIS PHARMACEUTICALS INC (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20030064492-A1 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICALS, INC. | 2003-04-03 | — | — | US | disclosed |
| US-20020177150-A1 | Derivatized oligonucleotides having improved uptake and other properties | ISIS PHARMACEUTICAL, INC. | 2002-11-28 | — | — | US | disclosed |
| EP-0804456-B1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 2002-08-21 | — | — | EP | disclosed |
| US-6395492-B1 | MONITORING CELLULAR INTAKE OF ADJUSTED NUCLEOSIDES; OBTAIN ORGANISM, INCUBATE WITH ADJUSTED NUCLEOSIDES, MONITOR CELL FOR REPORTER SIGNAL, PRESENCE INDICATES INTAKE | ISIS PHARMACEUTICALS, INC. | 2002-05-28 | — | — | US | disclosed |
| US-6153737-A | OLIGONUCLEOTIDES HAVING IMPROVED TRANSFER ACROSS CELLULAR MEMBRANES; FOR ASSAYING DISEASE STATES IN ANIMALS; HAVING IMPROVED TRANSFER AND UPTAKE PROPERTIES FOR TREATMENT OF DISEASES THROUGH MODULATION OF ACTIVITY OF DNA AND RNA | ISIS PHARMACEUTICALS, INC. (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0804456-A4 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS INC (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0804456-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996011205-A9 | PEPTIDE NUCLEIC ACID CONJUGATES | — | 1996-05-30 | — | — | WO | disclosed |
| WO-1996011205-A1 | PEPTIDE NUCLEIC ACID CONJUGATES | ISIS PHARMACEUTICALS, INC. (US) | 1996-04-18 | — | — | WO | disclosed |