Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29439072 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL38870 | 0.88 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL5352784 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL10905515 | 0.80 | ALDH1A1 (0.43) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL15881404 | 0.80 | ALDH1A1 (0.38) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL3485158 | 0.79 | KMT2A (0.49) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL16428359 | 0.78 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| Pyrene SCHEMBL27727552 | 0.76 | KMT2A (0.47) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL15389891 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 | |
| SCHEMBL9820389 | 0.76 | KMT2A (0.43) | ALDH1A1HPGDKMT2AKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729398-A | Compositions and methods for rapid identification of bacteria and fungi and phenotypic antimicrobial drug susceptibility testing | 豪夫迈·罗氏有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114286866-A | Compositions and methods for amplification and detection of hepatitis b viral RNA including HBV RNA transcribed from cccDNA | 豪夫迈·罗氏有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113785073-A | Preferential/selective amplification of RNA versus DNA targets using dITP based on strand isolation temperature | 豪夫迈·罗氏有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-113557307-A | Method for determining telomere-related variables and use thereof for diagnosis and/or prognosis of telomere-related diseases | 生命长度有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-105705660-B | Detection of single nucleotide polymorphisms using overlapping primers and melting probes | 豪夫迈·罗氏有限公司 | 2021-03-16 | — | — | CN | disclosed |