SCHEMBL3485202

SCHEMBL3485202

[S]Sc1nnnn1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.62
LMNA P02545 5/20 0.60
TSHR P16473 3/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HPGD P15428 1/20 0.60
MAPT P10636 3/20 0.57
POLB P06746 2/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
HTT P42858 2/20 0.55
GAA P10253 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
NPC1 O15118 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PKM P14618 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2395370 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL11202055 0.84 ALDH1A1 (0.73) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL17097394 0.83 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL6930563 0.81 ALDH1A1 (0.67) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL3485204 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL8094638 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL6930554 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL27438319 0.80 ALDH1A1 (0.57) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL10721861 0.79 ALDH1A1 (0.55) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL13542039 0.78 ALDH1A1 (0.58) ALDH1A1LMNATSHRSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100021480-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME PEPTRON CO., LTD (KR) 2010-01-28 US claimed
EP-1948676-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME Peptron Co., Ltd. (KR) 2008-07-30 EP claimed
WO-2007049940-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME PEPTRON CO., LTD (KR) 2007-05-03 WO claimed
WO-2007049941-A1 BIOACTIVE SUBSTANCE CARRIER FOR IN VIVO STABLE DELIVERY TEHREOF, CONJUGATE CONTAINING THE SAME, AND METHOD OF IN VIVO STABLE DELIVERY OF THE BIOACTIVE SUBSTANCE PEPTRON CO., LTD (KR) 2007-05-03 WO claimed
US-20100021480-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME PEPTRON CO., LTD (KR) 2010-01-28 US disclosed
EP-1948676-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME Peptron Co., Ltd. (KR) 2008-07-30 EP disclosed
WO-2007049941-A1 BIOACTIVE SUBSTANCE CARRIER FOR IN VIVO STABLE DELIVERY TEHREOF, CONJUGATE CONTAINING THE SAME, AND METHOD OF IN VIVO STABLE DELIVERY OF THE BIOACTIVE SUBSTANCE PEPTRON CO., LTD (KR) 2007-05-03 WO disclosed
WO-2007049940-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME PEPTRON CO., LTD (KR) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100021480-A1 BIOACTIVE SUBSTANCE-BLOOD PROTEIN CONJUGATE AND STABILIZATION OF A BIOACTIVE SUBSTANCE USING THE SAME SERPINA6, CSTB, PLG ALDH1A1 1756/4885LMNA 1097/4885TSHR 3136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.